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Kolbe-Schmitt Reaction. A base-promoted carboxylation of phenols that allows the synthesis of salicylic acid derivatives.
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Kolbe-Schmitt Reaction. A base-promoted carboxylation of phenols that allows the synthesis of salicylic acid derivatives.
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The Kolbe–Schmitt reaction or Kolbe process is a carboxylation chemical reaction that proceeds by heating sodium phenoxide with carbon dioxide under pressure, then treating the product with sulfuric acid. The final product is an aromatic hydroxy acid which is also known as salicylic acid.
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