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The reaction is named after the German chemist Siegmund Gabriel.
Potassium Phthalimide:----
Potassium Phthalimide is a chemical compound of formula C₈H₄KNO₂. It is the potassium salt of Phthalimide, and usually presents as fluffy, very pale yellow cryslals. It can be prepared by adding a hot solution of Phthalimide in ethanol to a solution of potassium hydroxide in ethanol; the desired product precipitates.
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The Gabriel synthesis is a substitution type Chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, the reaction uses potassium phthalimide.
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| Gabriel phthalimide synthesis |
The reaction is named after the German chemist Siegmund Gabriel.
Potassium Phthalimide:----
Potassium Phthalimide is a chemical compound of formula C₈H₄KNO₂. It is the potassium salt of Phthalimide, and usually presents as fluffy, very pale yellow cryslals. It can be prepared by adding a hot solution of Phthalimide in ethanol to a solution of potassium hydroxide in ethanol; the desired product precipitates.
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| Synthesis of primary amine, JACS, 1926 |
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